Paramedic Drug Facts: Ondanestron

Ondanestron

Trade Names: Zofran

Class: Antiemetic

Pharmacology:

Half life: 4hrs

Blocks the serotonin receptors in the CTZ, the stomach, and the small intestines.
Indications: Nausea and vomiting
Contraindications: known hypersensitivity
Cautions: use w/ caution in patients taking serotonin blockers
Dosage:

Adult: 4-8 mg IV/IO/PO
Pediatric: 0.5 mg/kg IV

Side Effects:

Headache
Lightheadedness
Dizziness

Special Considerations:

Pregnancy Safety: Category B