Trade Name: Nitrostat
Class: Vasodilator
Pharmacology:
Onset: 1-3 min
Duration: 30-60 min
Dilates arterioles and veins in the periphery, reduction of on preload, decrease in workload of the heart
Indications:
- Ischemic Chest Pain
- Congestive Heart Failure
- AMI
- Hypertensive emergencies with ACS
Contraindications:
- Hypersensitivity
- Hypotension
- Head injury
- Extreme bradycardia
- Extreme tachycardia
- Right ventricle infarction
- Cerebral hemorrhage
- Recent use of viagra type medications
- Aortic stenosis
Precautions:
Other vasodilators may have additive hypotensive effects
Do not mix with other drugs
Dosages:
- Tablet: 0.3-0.4 mg sl may repeat for a total of 3 doses at 5 min intervals
- Metered Spray: 1-2 sprays (0.4 mg/dose) for 0.5-1 sec at 5 min intervals
- Infusion: Begin at rate of 10 mcg/min increase by 10 mcg/min every 3-5 min cieling dose of 200 mcg/min
Side Effects:
- Headache
- Reflex tachycardia
- Hypotension
- Nausea and vomiting
- Postural syncope
- Diaphoresis
- Flushing